Determination of the effect of pyocyanin and Saccharomyces boulardii on gut microbiota and TLR4/MyD88/NF-κB and NLRP3 signaling pathways in sepsis induced by cecal ligation and puncture in rats

Abstract Sepsis is a life-threatening systemic inflammatory condition marked by a dysregulated host response to infection. The intestinal microbiota plays a pivotal role in maintaining immune homeostasis and epithelial barrier integrity, whereas dysbiosis significantly contributes to the pathogenesi...

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Bibliografiska uppgifter

Huvudupphov:	Mahmut Ucar, Ozgur Celebi, Demet Celebi, Sumeyye Baser, Mustafa Can Guler, Ayhan Tanyeli, Metin Kılıclıoglu, Ahmet Yılmaz, Serkan Yıldırım
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2025-07-01
Serie:	BMC Infectious Diseases
Ämnen:	Gut microbiota Saccharomyces boulardii Sepsis Pyocyanin Western blot
Länkar:	https://doi.org/10.1186/s12879-025-11308-4
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