The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas

Testicular germ cell tumors (GCTs) are stratified into seminomas and nonseminomas. Seminomas share many histological and molecular features with primordial germ cells, whereas the nonseminoma stem cell population—embryonal carcinoma (EC)—is pluripotent and thus able to differentiate into cells of al...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Margaretha A. Skowron, Teresa K. Becker, Lukas Kurz, Sina Jostes, Felix Bremmer, Florian Fronhoffs, Kai Funke, Gamal A. Wakileh, Melanie R. Müller, Aaron Burmeister, Thomas Lenz, Anja Stefanski, Kai Stühler, Patrick Petzsch, Karl Köhrer, Peter Altevogt, Peter Albers, Glen Kristiansen, Hubert Schorle, Daniel Nettersheim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-02-01
coleção:	Molecular Oncology
Assuntos:	CD24 differentiation embryonal carcinoma epigenetics germ cell tumors microenvironment
Acesso em linha:	https://doi.org/10.1002/1878-0261.13066
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!