IFITM1 and IFITM3 cooperate to restrict virus entry in endolysosomes

ABSTRACT Interferon-induced transmembrane (IFITM) proteins restrict virus infections at the stage of cellular entry. We previously characterized a GxxxG motif in the CD225 domain of human IFITM3 that mediates its multimerization, which is essential for the reduction of membrane fluidity by IFITM3 an...

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Үндсэн зохиолчид:	Isaiah Wilt, Abigail A. Jolley, Kazi Rahman, Kin Kui Lai, Mahesh Agarwal, Guoli Shi, Thorkell Andresson, Alex A. Compton
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2026-07-01
Цуврал:	Journal of Virology
Нөхцлүүд:	innate immunity IFITM interferons membrane transport RNA virus influenza
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/jvi.00677-26
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!