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Dipeptidyl peptidase-4 inhibitory potentials of Glycyrrhiza uralensis and its bioactive compounds licochalcone A and licochalcone B: An in silico and in vitro study

Type 2 diabetes mellitus (T2DM) is a growing global public health issue, and dipeptidyl peptidase-4 (DPP-4) is a potential therapeutic target in T2DM. Several synthetic anti-DPP-4 medications can be used to treat T2DM. However, because of adverse effects, there is an unmet demand for the development...

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Principais autores: Sibhghatulla Shaikh, Shahid Ali, Jeong Ho Lim, Hee Jin Chun, Khurshid Ahmad, Syed Sayeed Ahmad, Ye Chan Hwang, Ki Soo Han, Na Ri Kim, Eun Ju Lee, Inho Choi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-09-01
Serier:Frontiers in Molecular Biosciences
Fag:
type 2 diabetes mellitus
dipeptidyl peptidase-4
Glycyrrhiza uralensis
natural compounds
licochalcone A
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1024764/full
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