The MAB_3513c gene plays a key role in intrinsic resistance of Mycobacterium abscessus to isoniazid and ethionamide

ABSTRACT Isoniazid (INH) and ethionamide (ETH) are important antitubercular analogs that inhibit mycolic acid synthesis. However, Mycobacterium abscessus (M. abscessus) exhibits intrinsic resistance to both drugs. The molecular mechanisms underlying this resistance remain poorly understood. We ident...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Shuai Wang, Xiaofan Zhang, Xiange Fang, H. M. Adnan Hameed, Abdul Malik, Lihua Long, Yamin Gao, Cuiting Fang, Xirong Tian, Jinxing Hu, Xingyue Wang, Liqiang Feng, Tianyu Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-01-01
Colecção:	Microbiology Spectrum
Assuntos:	Mycobacterium abscessus isoniazid ethionamide intrinsic resistance nudC
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.02889-25
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!