Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells

Type I (α and β) and type III (λ) interferons (IFNs) induce the expression of a large set of antiviral effector molecules via their respective surface membrane receptors. Whereas most cell types respond to type I IFN, type III IFN preferentially acts on epithelial cells and protects mucosal organs s...

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Principais autores:	Tharini A. Selvakumar, Sudeep Bhushal, Ulrich Kalinke, Dagmar Wirth, Hansjörg Hauser, Mario Köster, Mathias W. Hornef
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-10-01
coleção:	Frontiers in Immunology
Assuntos:	interferon-lambda intestinal epithelium interleukin 28 receptor transcription gastrointestinal tract
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01302/full
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