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Tween 80 containing lipid nanoemulsions for delivery of indinavir to brain

Indinavir is a protease inhibitor used in the treatment of HIV infection. However, it has limited efficacy in eradicating the virus in the brain due to efflux by P-glycoprotein (P-gp) expressed at the blood–brain barrier (BBB). The objective of this work was to develop an o/w lipid nanoemulsion (LNE...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kandadi Prabhakar, Syed Muzammil Afzal, Goparaboina Surender, Veerabrahma Kishan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2013-09-01
Rangatū:Acta Pharmaceutica Sinica B
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211383513000774
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