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Computational model of the full-length TSH receptor

(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves’ disease) caused by stimulating TSHR antibodies. To date, only one domain of the extracellular region of the TSHR has been crystalli...

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Gardado en:
Principais autores: Mihaly Mezei, Rauf Latif, Terry F Davies
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Assuntos:
TSHR
transmembrane domain
molecular dynamics
hinge region
linker region
TSH
Acceso en liña:https://elifesciences.org/articles/81415
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