Targeting endoplasmic reticulum export disrupts metabolic resilience in multiple myeloma

Abstract Multiple myeloma (MM) is characterized by the production and secretion of large quantities of immunoglobulins, making this malignancy highly dependent on mechanisms that maintain cellular proteostasis. While significant clinical progress has been made by targeting the degradative branch of...

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Bibliografiske detaljer

Principais autores:	Utku Horzum, Herbert Oberacher, Margot Haun, Stephan Geley, Monica Roman-Trufero, Holger Auner, Agnieszka Martowicz, Gerold Untergasser, Eberhard Gunsilius, Wolfgang Willenbacher, Hamdullah Yanik, Gunes Esendagli, Dominik Wolf, Hesso Farhan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2026-07-01
Serier:	Signal Transduction and Targeted Therapy
Online adgang:	https://doi.org/10.1038/s41392-026-02833-y
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