Inhibition of macrophage migration inhibitory factor attenuates bleomycin-induced murine pulmonary fibrosis via the MAPK pathway

Abstract Background Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive disease marked by excessive extracellular matrix deposition and deteriorating lung function. Although macrophage migration inhibitory factor (MIF) has been implicated in pulmonary fibrosis, the downstream mechanisms—par...

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Detalhes bibliográficos

Principais autores:	Jingwei Wang, Wei Zhao, Nafeisa Dilixiati, Yuanying Wang, Yawen Song, Qiao Ye
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-05-01
coleção:	Respiratory Research
Assuntos:	Macrophage migration inhibitory factor CD74 Idiopathic pulmonary fibrosis Pulmonary fibrosis Single-cell RNA sequencing MAPK
Acesso em linha:	https://doi.org/10.1186/s12931-026-03722-2
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