P2X4 signalling contributes to hyperactivity but not pain sensitization comorbidity in a mouse model of attention deficit/hyperactivity disorder

Introduction: Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by hyperactivity, inattention, and impulsivity that often persist until adulthood. Frequent comorbid disorders accompany ADHD and two thirds of children diagnosed with ADHD also suffer...

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Hlavní autoři:	Sarah Bou Sader Nehme, Sandra Sanchez-Sarasua, Ramy Adel, Marie Tuifua, Awatef Ali, Amina E. Essawy, Sherine Abdel Salam, Walid Hleihel, Eric Boué-Grabot, Marc Landry
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-01-01
Edice:	Frontiers in Pharmacology
Témata:	attention deficit/hyperactivity disorders pain sensitization purines P2X4 anterior cingulate cortex posterior insula
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1288994/full
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