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From GWAS variant to function: A study of ∼148,000 variants for blood cell traits

Summary: Genome-wide association studies (GWASs) have identified hundreds of thousands of genetic variants associated with complex diseases and traits. However, most variants are noncoding and not clearly linked to genes, making it challenging to interpret these GWAS signals. We present a systematic...

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Principais autores: Quan Sun, Cheynna A. Crowley, Le Huang, Jia Wen, Jiawen Chen, Erik L. Bao, Paul L. Auer, Guillaume Lettre, Alexander P. Reiner, Vijay G. Sankaran, Laura M. Raffield, Yun Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
coleção:HGG Advances
Assuntos:
genome-wide association studies
variant to function
functional annotations
experimental validations
blood cell traits
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666247721000440
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