Expanding the binding specificity for RNA recognition by a PUF domain
The PUF RNAbinding domain has an eight-repeat structure with the ability to bind an eight-base RNA sequence. Here the authors generate a comprehensive library of variants of a PUF domain to find an RNA binding code and design PUF domains that recognize an arbitrary RNA sequence.
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2021-08-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-021-25433-6 |
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