AI-powered omics-based drug pair discovery for pyroptosis therapy targeting triple-negative breast cancer

Abstract Due to low success rates and long cycles of traditional drug development, the clinical tendency is to apply omics techniques to reveal patient-level disease characteristics and individualized responses to treatment. However, the heterogeneous form of data and uneven distribution of targets...

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Bibliographic Details

Main Authors:	Boshu Ouyang, Caihua Shan, Shun Shen, Xinnan Dai, Qingwang Chen, Xiaomin Su, Yongbin Cao, Xifeng Qin, Ying He, Siyu Wang, Ruizhe Xu, Ruining Hu, Leming Shi, Tun Lu, Wuli Yang, Shaojun Peng, Jun Zhang, Jianxin Wang, Dongsheng Li, Zhiqing Pang
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2024-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-024-51980-9
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