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An Improved 2-Aminoimidazole Based Anti-Biofilm Coating for Orthopedic Implants: Activity, Stability, and in vivo Biocompatibility

Orthopedic device-related infections remain a serious challenge to treat. Central to these infections are bacterial biofilms that form on the orthopedic implant itself. These biofilms shield the bacteria from the host immune system and most common antibiotic drugs, which renders them essentially ant...

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Detalhes bibliográficos
Principais autores: Guglielmo Attilio Coppola, Jolien Onsea, T. Fintan Moriarty, Dirk Nehrbass, Caroline Constant, Stephan Zeiter, Merve Kübra Aktan, Annabel Braem, Erik V. Van der Eycken, Hans P. Steenackers, Willem-Jan Metsemakers
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-04-01
coleção:Frontiers in Microbiology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2021.658521/full
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