Cyclooxygenase Isoform Exchange Blocks Brain-Mediated Inflammatory Symptoms.

Cyclooxygenase-2 (COX-2) is the main source of inducible prostaglandin E2 production and mediates inflammatory symptoms including fever, loss of appetite and hyperalgesia. COX-1 is dispensable for fever, anorexia and hyperalgesia but is important for several other functions both under basal conditio...

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Autors principals:	Daniel Björk Wilhelms, Elahe Mirrasekhian, Joanna Zajdel, Anand Kumar Singh, David Engblom
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2016-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5115700?pdf=render
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