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Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.

The innate immune response mediated by cells such as natural killer (NK) cells is critical for the rapid containment of virus replication and spread during acute infection. Here, we show that subtype 11 of the type I interferon (IFN) family greatly potentiates the antiviral activity of NK cells duri...

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Principais autores: Kathrin Gibbert, Jara J Joedicke, Andreas Meryk, Mirko Trilling, Sandra Francois, Janine Duppach, Anke Kraft, Karl S Lang, Ulf Dittmer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS Pathogens
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912583/pdf/?tool=EBI
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