Upregulation of Cortical Renin and Downregulation of Medullary (Pro)Renin Receptor in Unilateral Ureteral Obstruction

Chronic kidney disease (CKD) is characterized by renal dysfunction, which is a common feature of other major diseases, such as hypertension and diabetes. Unilateral ureteral obstruction (UUO) has been used as a model of CKD in experimental animals and consists of total obstruction of one kidney uret...

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Autors principals:	Stefanny M. Figueroa, Mauricio Lozano, Carolina Lobos, Matthew T. Hennrikus, Alexis A. Gonzalez, Cristián A. Amador
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2019-11-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	chronic kidney disease intrarenal RAS unilateral ureter obstruction inflammation pro-renin receptor
Accés en línia:	https://www.frontiersin.org/article/10.3389/fphar.2019.01314/full
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