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Lipopolysaccharide induces neuroinflammation in a valproic acid male model of autism

Background: Autism spectrum disorders (ASD) are characterized by social skill deficits and behavior impairments. Exposure to valproic acid (VPA) has been linked to ASD in humans and ASD-like behaviors in rodents. Clinical evidence suggests that immunological damage can worsen ASD symptoms in humans....

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Principais autores: Junhong Jiang, Ling Zhang, De Wu, Dongjun Zhao, Songcheng Ying, Shenggang Ding
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-01-01
coleção:Brain Research Bulletin
Assuntos:
Autism
Male rat model
Valproic acid
Lipopolysaccharide
Neuroinflammation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0361923024002880
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