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Fluvoxamine and lycopene alleviate cisplatin-induced kidney fibrosis by modulating miR-21 and fibrotic signaling pathways

Abstract Cisplatin (Cis) is a widely utilized chemotherapy drug for managing various cancers, but its efficacy is limited by nephrotoxicity, which frequently results in kidney fibrosis. Oxidative stress, inflammation, and the fibrotic transforming growth factor beta/small mothers against decapentapl...

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Bibliografische Detailangaben
Hauptverfasser: Sally E. Abu-Risha, Samia S. Sokar, Mai A. Mousa, Nagla A. El-Shitany, Alaa E. Elsisi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-06-01
Schriftenreihe:Scientific Reports
Schlagworte:
Online-Zugang:https://doi.org/10.1038/s41598-026-55689-1
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