Serum microbiome-related metabolites—including short-chain fatty acids and indole derivatives—predict outcome and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a two-timepoint LC–MS study

BackgroundDelayed cerebral ischemia (DCI) remains a major determinant of poor outcome after aneurysmal subarachnoid hemorrhage (aSAH). Growing evidence suggests that gut microbiota–derived metabolites, including short-chain fatty acids (SCFAs) and tryptophan-related indole compounds, modulate neuroi...

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Autori principali:	Blanka Nagybanyai-Nagy, Roland Tengölics, Csilla Sajben, Dominika Olasz, Attila Schwarcz, Tihamer Molnar, Peter Csecsei
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-04-01
Serie:	Frontiers in Neurology
Soggetti:	aneurysmal subarachnoid hemorrhage delayed cerebral ischemia indole-3-propionic acid outcome short-chain fatty acids tryptophan
Accesso online:	https://www.frontiersin.org/articles/10.3389/fneur.2026.1768108/full
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