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The regulatory mechanisms of IGF1 in the osteogenic differentiation of canine MSMSCs via BMP2-Smad1/5 signaling pathway

Objective To investigate the role of the bone morphogenetic protein 2 (BMP2)-Smad1/5 and p38MAPK signaling pathways in the osteogenic differentiation of MSMSCs by insulin-like growth factor 1 (IGF1).Methods A recombinant adenovirus (RAD) and IGF1 expressing IGF1 gene were constructed. After osteogen...

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Principais autores: LIAO Chunhui, LI Mingfei, YE Jinmei, PENG Wei, CHEN Songling
Formato: Artigo
Idioma:Chinês
Publicado: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2020-01-01
Series:口腔疾病防治
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Acceso en liña:http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.01.003
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