Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

ABSTRACT Intestinal fibrosis can progress independently of inflammation, driven by a self‐perpetuating cycle of extracellular matrix (ECM)‐myofibroblast interactions. However, due to the lack of reliable therapeutic targets within the ECM, the current strategy predominantly focuses on intracellular...

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Detalhes bibliográficos

Principais autores:	Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-04-01
coleção:	Advanced Science
Assuntos:	Crohn's disease extracellular matrix fibronectin fibrosis
Acesso em linha:	https://doi.org/10.1002/advs.202519433
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