GM-CSF promotes pro-inflammatory macrophage activation associated with Akt/mTOR signaling during experimental colitis

BackgroundUlcerative colitis (UC) is an intestinal immune disorder of unknown etiology. Mounting evidence reveals a central role of macrophages in the hemostatic balance of gut immunity, and dysfunctional macrophages are associated with UC pathogenesis. Granulocyte macrophage-colony stimulating fact...

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Bibliografski detalji

Glavni autori:	Silan Shen, Kexin Chen, Lili Li, Mingshan Jiang, Yongbin Jia, Xiufeng Bai, Zhen Zeng, Chunxiang Ma, Yuan Dang, Kehan Hu, Yanqiong Chen, Wenting Zhang, Zhiyong Miao, Linlin Chen, Hu Zhang
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-06-01
Serija:	Frontiers in Immunology
Teme:	Akt glycolysis granulocyte macrophage-colony stimulating factor macrophages mTOR ulcerative colitis
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1799536/full
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