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The somatic mutation landscape of the human body

Abstract Background Somatic mutations in healthy tissues contribute to aging, neurodegeneration, and cancer initiation, yet they remain largely uncharacterized. Results To gain a better understanding of the genome-wide distribution and functional impact of somatic mutations, we leverage the genomic...

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Bibliografske podrobnosti
Principais autores: Pablo E. García-Nieto, Ashby J. Morrison, Hunter B. Fraser
Format: Artigo
Jezik:Inglês
Izdano: BMC 2019-12-01
Serija:Genome Biology
Teme:
Online dostop:https://doi.org/10.1186/s13059-019-1919-5
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