Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis

Abstract Over the past two decades a number of studies have demonstrated activity of the retroviral enzyme reverse transcriptase in the serum of patients with sporadic amyotrophic lateral sclerosis (ALS). Known human exogenous retroviruses such as HIV-1 have been eliminated as possible sources of th...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Jeremy A. Garson, Louise Usher, Ammar Al-Chalabi, Jim Huggett, Edmund F. Day, Adele L. McCormick
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2019-03-01
श्रृंखला:	Acta Neuropathologica Communications
विषय:	Amyotrophic lateral sclerosis ALS Human endogenous retrovirus HERV-K HERV-W RNA
ऑनलाइन पहुंच:	http://link.springer.com/article/10.1186/s40478-019-0698-2
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