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The mTOR signaling pathway mediates the phenotypic switch between adipocytes and osteocytes in mice with obesity-related osteoporosis

Abstract Background Obesity-related osteoporosis is a metabolic disorder of the adipose tissue and bone caused by energy accumulation. The role of adipogenic and osteogenic differentiation and phenotypic transformation in the pathogenesis of osteoporosis and the relevant signaling mechanism are stil...

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Principais autores: Chuanjie Liang, Yan Guo, Yongliang Liu, Yangjunjie Wang, Jing Xiao, Haiying Li, Xinxin Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-08-01
coleção:European Journal of Medical Research
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Acesso em linha:https://doi.org/10.1186/s40001-025-02954-0
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