A rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhabditis elegans.

Mitochondrial DNA (mtDNA) encodes respiratory complex subunits essential to almost all eukaryotes; hence respiratory competence requires faithful duplication of this molecule. However, the mechanism(s) of its synthesis remain hotly debated. Here we have developed Caenorhabditis elegans as a convenie...

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Autors principals:	Samantha C Lewis, Priit Joers, Smaranda Willcox, Jack D Griffith, Howard T Jacobs, Bradley C Hyman
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2015-02-01
Col·lecció:	PLoS Genetics
Accés en línia:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004985&type=printable
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