Oral curative therapeutic study of N-nitrosodiethylamine-induced mouse liver damage of chitosan-coated ursolic acid niosomes

Abstract Ursolic acid (UA), classified as a Biopharmaceutics Classification System (BCS) class IV compound, exhibits hepatoprotective, anti-inflammatory, and anticancer activities. In previous studies, niosomes have been shown to increase the bioavailability of BCS class IV drugs. Chitosan coating a...

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Autors principals:	Andang Miatmoko, Ahmad Aziz Jauhari, Amelia Anneke Faradisa, Devy Maulidya Cahyani, Berlian Sarasitha Hariawan, Joni Susanto, Thaigarajan Parumasivam, Esti Hendradi, Retno Sari
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-06-01
Col·lecció:	Scientific Reports
Matèries:	Anticancer Ursolic acid Niosome Liver damage NDEA Curative
Accés en línia:	https://doi.org/10.1038/s41598-025-04571-7
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