Long-term safety and efficacy of deoxycytidine/deoxythymidine in treatment of POLG-related disorders

We evaluated the safety and efficacy of enteral deoxycytidine/deoxythymidine combination therapy in treatment of POLG-related disorders, genetic mitochondrial diseases characterized by progressive neurological degeneration. A single-centre open-label phase II trial was conducted. Inclusion criteria...

Descripció completa

Dades bibliogràfiques

Autors principals:	Anthony C.T. Cheung, Saoussen Berrahmoune, Christelle Dassi, Heather Pekeles, Tommy Gagnon, Paula J. Waters, Ralf Eberhard, Daniela Buhas, Kenneth A. Myers
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-07-01
Col·lecció:	Neurotherapeutics
Matèries:	DNA polymerase gamma POLG Deoxynucleoside Mitochondrial disorder Mitochondrial DNA depletion disorder
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1878747926001157
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!