Clinacanthus nutans (Burm.f.) Lindau facilitates cuproptosis and ameliorates colon cancer progression by inhibiting PDE3B-mediated Apelin pathway

Abstract Background Colon cancer, a prevalent malignancy occurs in the gastrointestinal tract with annually increasing incidence and mortality, and Clinacanthus nutans (Burm.f.) Lindau (CN) possesses anticancer activity in a wide spectrum of tumors. This investigation aims at illuminating potential...

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Huvudupphov:	Gaoyun Zhou, Xueying Lin, Zhiheng Lai, Dewen Su, Long Lin, Xuewu Chen
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Springer 2025-08-01
Serie:	Discover Oncology
Ämnen:	Clinacanthus nutans (Burm.f.) Lindau Colon cancer PDE3B Cuproptosis Apelin pathway
Länkar:	https://doi.org/10.1007/s12672-025-02037-w
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