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Endoplasmic reticulum stress in lung cancer

Endoplasmic reticulum is the primary site of eukaryotic cells involved in biosynthesis, lipid metabolism, glucose metabolism, protein folding and secretion. Multiple factors in the tumor microenvironment may induce the accumulation of unfolded and misfolded proteins in the endoplasmic reticulum and...

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Principais autores: Donghuan Zhang, Lanlan Lin, Hui Jin, Huajun Mao, Luying Wang, Wenwen Ma, Zhenghong Lao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-09-01
coleção:Frontiers in Oncology
Assuntos:
lung cancer
tumor microenvironment
endoplasmic reticulum stress
unfolded protein response
targeted therapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2025.1550075/full
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