Structural and functional profiling of the human histone methyltransferase SMYD3.
The SET and MYND Domain (SMYD) proteins comprise a unique family of multi-domain SET histone methyltransferases that are implicated in human cancer progression. Here we report an analysis of the crystal structure of the full length human SMYD3 in a complex with an analog of the S-adenosyl methionine...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2011-01-01
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| Schriftenreihe: | PLoS ONE |
| Online-Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21779408/pdf/?tool=EBI |
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