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Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia

Abstract: T-cell acute lymphoblastic leukemia (T-ALL) expands in various bone marrow (BM) sites of the body. We investigated whether different BM sites could differently modulate T-ALL propagation using in vivo animal models. We observed that mouse and human T-ALL develop slowly in the BM of tail ve...

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Huvudupphov: Xavier Cahu, Julien Calvo, Sandrine Poglio, Nais Prade, Benoit Colsch, Marie-Laure Arcangeli, Thierry Leblanc, Arnaud Petit, Frederic Baleydier, Andre Baruchel, Judith Landman-Parker, Christophe Junot, Jerome Larghero, Paola Ballerini, Eric Delabesse, Benjamin Uzan, Francoise Pflumio
Materialtyp: Artigo
Språk:Inglês
Utgiven: Elsevier 2017-09-01
Serie:Blood Advances
Länkar:http://www.sciencedirect.com/science/article/pii/S2473952920303177
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