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To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2

To be, or not to be, that is the question. (William Shakespeare, Hamlet)Endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and ERAP2, respectively) play a role in trimming peptides that are too long to be bound and presented by class I HLA (HLA-I) molecules to CD8+ T cells. They may also affect th...

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Bibliografski detalji
Glavni autor: Piotr Kuśnierczyk
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-06-01
Serija:Frontiers in Immunology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.902567/full
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