Senescent Stroma-Derived Glutamine: A Driver of Aggressiveness in Prostate and Ovarian Cancer Cells

Cancer progression is influenced by the dynamic interplay between tumor cells and the surrounding stromal microenvironment. Therapy-induced senescence (TIS) of stromal fibroblasts represents a common outcome of anticancer treatments, contributing to tumor progression through the senescence-associate...

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Detalhes bibliográficos

Principais autores:	Giulia Lori, Caterina Mancini, Caterina Paffetti, Dayana Desideri, Erica Pranzini, Alice Santi, Manuela Leri, Alessio Biagioni, Matteo Benelli, Pietro Spatafora, Fedele Maria Manicone, Flavia Sorbi, Angela Leo, Massimiliano Fambrini, Sergio Serni, Francesca Magherini, Maria Letizia Taddei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-04-01
coleção:	Cells
Assuntos:	therapy-induced senescence fibroblasts glutamine metabolism cancer cell invasion NRF2/ETS1 signaling
Acesso em linha:	https://www.mdpi.com/2073-4409/15/9/770
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