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Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.

While the role of estrogen receptor-related receptor alpha (ERRα) in chondrogenesis has been investigated, the involvement of ERR gamma (ERRγ) has not been determined. To assess the effect of increased ERRγ activity on cartilage development in vivo, we generated two transgenic (Tg) lines overexpress...

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Principais autores: Marco Cardelli, Ralph A Zirngibl, Jonathan F Boetto, Kristen P McKenzie, Tammy-Claire Troy, Kursad Turksen, Jane E Aubin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3857204?pdf=render
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