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Stimuli-responsive polypeptide nanogels for trypsin inhibition

A new type of hydrophilic, biocompatible, and biodegradable polypeptide nanogel depots loaded with the natural serine protease inhibitor α1-antitrypsin (AAT) was applied for the inhibition of the inflammatory mediator trypsin. Two types of nanogels were prepared from linear synthetic polypeptides ba...

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Autori principali: Petr Šálek, Jana Dvořáková, Sviatoslav Hladysh, Diana Oleshchuk, Ewa Pavlova, Jan Kučka, Vladimír Proks
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2022-06-01
Serie:Beilstein Journal of Nanotechnology
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Accesso online:https://doi.org/10.3762/bjnano.13.45
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