Bitter Taste Receptors (TAS2Rs) in Human Lung Macrophages: Receptor Expression and Inhibitory Effects of TAS2R Agonists

BackgroundBitter-taste receptors (TAS2Rs) are involved in airway relaxation but are also expressed in human blood leukocytes. We studied TAS2R expression and the effects of TAS2R agonists on the lipopolysaccharide (LPS)-induced cytokine release in human lung macrophages (LMs).MethodsLung macrophages...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Stanislas Grassin-Delyle, Hélène Salvator, Nikola Mantov, Charlotte Abrial, Marion Brollo, Christophe Faisy, Emmanuel Naline, Louis-Jean Couderc, Philippe Devillier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-10-01
coleção:	Frontiers in Physiology
Assuntos:	bitter taste receptor human lung macrophage parenchyma explant cytokine inflammation
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphys.2019.01267/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!