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Butyrophilins: γδ T Cell Receptor Ligands, Immunomodulators and More

Butyrophilins (BTN) are relatives of the B7 family (e.g., CD80, PD-L1). They fulfill a wide range of functions including immunomodulation and bind to various receptors such as the γδ T cell receptor (γδTCR) and small molecules. One intensively studied molecule is BTN3A1, which binds via its cytoplas...

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Autors principals: Thomas Herrmann, Mohindar M. Karunakaran
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-03-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2022.876493/full
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