LARGE DELETIONS IN THE F8 GENE PREDICT IMMUNE TOLERANCE INDUCTION FAILURE IN PEOPLE WITH SEVERE HEMOPHILIA A

Immune Tolerance Induction (ITI) is the only treatment to eradicate inhibitors in people with Severe Hemophilia A (SHA). Successful ITI restores Factor VIII (FVIII) tolerance. ITI is demanding and successful in approximately 70% of people. Therefore, identifying predictors of ITI outcome is essentia...

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Autors principals:	I Oomen, A Abdi, L Broer, RM Camelo, FMRA Callado, LEM Carvalho, IL Calcaterra, M Carcao, G Castaman, JCJ Eikenboom, K Fischer, VKB Franco, J Geissler, TW Kuijpers, FWG Leebeek, D Lillicrap, CS Lorenzato, ME Mancuso, D Matino, MND Di Minno, A Mo, AB Mohseny, SQ Nagelkerke, J Oldenburg, SM Rezende, K Fijnvandraat, S Gouw
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-10-01
Col·lecció:	Hematology, Transfusion and Cell Therapy
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S253113792401280X
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