Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts

Background:Mycobacterium tuberculosis (MTB) has limited ability to acquire variability. Analysis of its microevolution might help us to evaluate the pathways followed to acquire greater infective success. Whole-genome sequencing (WGS) in the analysis of the transmission of MTB has elucidated the mag...

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Detalhes bibliográficos

Principais autores:	Marta Herranz, Ilva Pole, Iveta Ozere, Álvaro Chiner-Oms, Miguel Martínez-Lirola, Felipe Pérez-García, Paloma Gijón, María Jesús Ruiz Serrano, Laura Clotet Romero, Oscar Cuevas, Iñaki Comas, Emilio Bouza, Laura Pérez-Lago, Darío García-de-Viedma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-01-01
coleção:	Frontiers in Microbiology
Assuntos:	tuberculosis variability whole genome sequencing SNPs microevolution
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fmicb.2017.02661/full
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