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Evaluating the efficacy and safety of milrinone for prevention of post-patent ductus arteriosus closure syndrome (the MIDAS trial) in extremely preterm infants: a multicentre, double-masked, randomised, placebo-controlled trial

Introduction Post-ligation cardiac syndrome (PLCS) represents a state of severe post-intervention cardiopulmonary instability, seen in up to 50% of extremely premature infants after surgical closure of the patent ductus arteriosus (PDA); yet an evidence-based approach to treatment of this condition...

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Hauptverfasser: Anup C Katheria, Abhik Das, Susan R Hintz, Edward F Bell, Tarah T Colaizy, Karen J Johnson, Cheryl Battersby, Philip T Levy, Matthew M Laughon, Felix Ines, Patrick J McNamara, Shazia Bhombal, Valerie Y Chock, Heidi M Harmon, Matthew A Rysavy, Adrianne Rahde-Bischoff, Jenna Gabrio, Diana Montoya-Williams, Keira Sorrells, Ben Carper
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2025-08-01
Schriftenreihe:BMJ Open
Online-Zugang:https://bmjopen.bmj.com/content/15/8/e105018.full
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