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Role of biotransformation in the diazinon-induced toxicity in HepG2 cells and antioxidant protection by tetrahydrocurcumin

Diazinon (DZN) is an insecticide extensively used to control pests in crops and animals. However, its indicriminated use may lead to liver damage in animals and humans. This study aimed to evaluate the toxicity of DZN (25–150 µM) on human hepatoblastoma (HepG2) cells after 24 and 48 h of exposure an...

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Hoofdauteurs: Camila Araújo Miranda, Eduardo Morais Beretta, Layra Araújo Ferreira, Emmily Sousa da Silva, Beatriz Zimermano Coimbra, Priscila Tartari Pereira, Raul Ghiraldelli Miranda, Daniel Junqueira Dorta, Flávia Thomaz Verechia Rodrigues, Fábio Erminio Mingatto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2023-01-01
Reeks:Toxicology Reports
Onderwerpen:
HepG2 cell line
Organophosphorus insecticides
Toxicity
RONS
Antioxidants
Online toegang:http://www.sciencedirect.com/science/article/pii/S2214750022002311
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