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From periodontal infection to oral–systemic dysbiosis: re-framing the oral microbiome’s role in systemic health and the prophylactic potential of Streptococcus salivarius probiotics

Since the late 19th century, the relationship between oral infections and systemic health has been widely debated. Recent advances in microbiome research suggest that oral microbial imbalance—dysbiosis—can contribute to systemic inflammatory and metabolic disorders. We propose that the term “oral-sy...

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Autori principali: Francesco Di Pierro, Carlo Fornaini, Chiara Maria Palazzi, Alexander Bertuccioli, John Tagg, Nicola Zerbinati
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-12-01
Serie:Frontiers in Microbiology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1685071/full
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