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High-resolution population structure and runs of homozygosity reveal the genetic architecture of complex traits in the Lipizzan horse

Abstract Background The sample ascertainment bias due to complex population structures remains a major challenge in genome-wide investigations of complex traits. In this study we derived the high-resolution population structure and levels of autozygosity of 377 Lipizzan horses originating from five...

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Principais autores: Gertrud Grilz-Seger, Thomas Druml, Markus Neuditschko, Max Dobretsberger, Michaela Horna, Gottfried Brem
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-03-01
coleção:BMC Genomics
Assuntos:
Lipizzan horse
Runs of homozygosity (ROH)
ROH islands
NetView
Melanoma
HOXB cluster, selection signature
Acesso em linha:http://link.springer.com/article/10.1186/s12864-019-5564-x
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