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The LKB1–AMPK Signaling Axis Modulates Ferroptosis in Fibroblast-Like Synoviocytes Derived from Rheumatoid Arthritis

Background/Objectives: Ferroptosis is a type of regulated cell death that involves iron-dependent accumulation of lipid peroxides. Because fibroblast-like synoviocytes (FLSs) in patients with rheumatoid arthritis (RA) have a hyperplastic and inflammatory phenotype, selective induction of FLS cell de...

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Principais autores: Ha-Reum Lee, Su-Jin Yoo, Jinhyun Kim, Seong Wook Kang
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-01-01
Serija:Biomedicines
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Online dostop:https://www.mdpi.com/2227-9059/13/2/321
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