Structural Insights into Ligand—Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors

G protein-coupled receptors (GPCRs) are versatile signaling proteins that mediate complex cellular responses to hormones and neurotransmitters. Ligand directed signaling is observed when agonists, upon binding to the same receptor, trigger significantly different configuration of intracellular event...

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Autori principali:	Krzysztof Jóźwiak, Anita Płazińska
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-02-01
Serie:	Molecules
Soggetti:	ligand directed signaling β-adrenergic receptors dopaminergic receptors muscarinic receptors serotonin receptors opioid receptors
Accesso online:	https://www.mdpi.com/1420-3049/26/4/851
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