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Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

Abstract Background Pancreatic cancer is susceptible to gemcitabine resistance, and patients receive less benefit from gemcitabine chemotherapy. Previous studies report that gambogic acid possesses antineoplastic properties; however, to our knowledge, there have been no specific studies on its effec...

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Principais autores: Guanggai Xia, Hongcheng Wang, Ziliang Song, Qingcai Meng, Xiuyan Huang, Xinyu Huang
Format: Artigo
Jezik:Inglês
Izdano: BMC 2017-08-01
Serija:Journal of Experimental & Clinical Cancer Research
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Online dostop:http://link.springer.com/article/10.1186/s13046-017-0579-0
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