Beyond hyperglycemia: histone modification-mediated epigenetic dysregulation in diabetic retinopathy and nephropathy

Abstract Diabetic retinopathy (DR) and diabetic nephropathy (DN) are major microvascular complications whose progression is often sustained despite glycemic normalization, consistent with metabolic memory. Accumulating evidence indicates that histone modification dysregulation provides a mechanistic...

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Bibliografische Detailangaben

Hauptverfasser:	Minxuan Tang, Hongyu Zhu, Suyan Li, Lei Qiao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	Diabetology & Metabolic Syndrome
Schlagworte:	Diabetic retinopathy Diabetic nephropathy Histone modification Epigenetics Metabolic memory Lactylation
Online-Zugang:	https://doi.org/10.1186/s13098-026-02129-9
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